To understand
osteoporosis, it is important to learn about the bone. Mainly of collagen, bone
is living, growing tissue. Collagen is a protein which provides a flexible
framework and the calcium phosphate mineral is one that adds strength and
harden the frame. This combination of collagen and calcium makes strong and
flexible enough bone to resist stress. Over 99 percent of the calcium in the
body is found in the bones and teeth. The remaining 1 percent is in the blood.
Two types of bone
found in the body-cortical and trabecular. Cortical bone is dense and compact.
The outer layer of the bone is formed. Trabecular bone which composes the inner
layer of the bone and has a spongy structure, honeycomb.
bone remodeling
Women, Men, and
osteoporosis
bone remodeling
Throughout life,
bone is constantly renewed by a two-part process called remodeling. This method
involves resorption and formation. During resorption, special cells called
osteoclasts break down and remove old bone. During bone formation, new bone is
planned to replace the old. Several hormones including calcitonin, parathyroid
hormone, vitamin D, estrogen (in women) and testosterone (in men), among
others, regulate osteoclast and osteoblast function.
The bank account
bone
Think bone like a
bank account where you "deposit" and "withdraw" bone.
During childhood and adolescence, new bone is added to the skeleton faster than
old bone is removed. As a result, bones become larger, heavier and more dense.
For most people, bone formation is proceeding at a faster rate than the removal
until bone mass peaks form during the third decade of life.
After 20 years, the
bones "withdrawals" may begin to exceed "deposits." For
many people, this bone loss can be prevented by continuing to get calcium,
vitamin D, and exercise and avoiding smoking and excessive alcohol consumption.
Osteoporosis develops when the removal of the bone occurs too quickly, the
replacement occurs too slowly, or both. You are more likely to develop
osteoporosis if you have not reached your maximum peak bone mass during your
bone building years.
Women, Men, and
osteoporosis
Women are more
likely than men to develop osteoporosis. This is because women generally have
smaller, thinner bones than men and because women can lose bone rapidly in the
first 4-8 years after menopause due to the sharp decline in the production of
estrogen hormone. Produced by the ovaries, estrogen has been shown to have a
protective effect on bone. Women usually go through menopause between 45 and 55
years after menopause, bone loss in women far exceeds that of men. However, by
age 65, men and women tend to lose bone at the same rate. Although men do not
experience the equivalent of menopause, the production of the male hormone
testosterone may decrease, and this can lead to increased bone loss and an
increased risk of developing osteoporosis.
Prevention of
osteoporosis
Osteoporosis is
preventable for many people. Prevention is important because even though there
are treatments for osteoporosis, a cure has not been found yet. A comprehensive
program that can help prevent osteoporosis include:
bearing exercise
a healthy lifestyle
without smoking or excessive alcohol consumption
bone density tests………..drugs,
if appropriate
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